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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 433359Generated: October 27, 2026

(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoic acid → 4-(N'-(3,5-Difluorophenylacetyl)-L-alaninyl)amino-1,1-dimethyl-3-isochromanone

https://huagongshe.com/reaction/433359

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoic acidHCID 12135350—
Reactant4-Amino-1,1-dimethyl-3-isochromanoneHCID 22312041—
Product4-(N'-(3,5-Difluorophenylacetyl)-L-alaninyl)amino-1,1-dimethyl-3-isochromanoneHCID 10158833—

Reaction Steps

Following General Procedure A above using N-(3,5-difluorophenylacetyl)-L-alanine and 4-amino-1,1-dimethyl-3-isochromanone, the title compound could be prepared.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06667305B1
Source datasetuspto-grants-2003_12
ORD IDord-87b25a8f31b54f8c85bcf9152ef9d975
Source noteuspto-grants-2003_12