HuagongsheHuagongshe Chemistry Print Report · For research reference only
Allyl Alcohol → N-(3,4dichlorophenyl)alanine Allyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Allyl Alcohol | HCID 7858 | — |
| Reactant | N-(3,4-dichlorophenyl)alanine Methyl Ester | HCID 54289412 | — |
| Product | N-(3,4dichlorophenyl)alanine Allyl Ester | HCID 53861976 | — |
Reaction Steps
Following transesterification General Procedure AB above and using N-(3,4-dichlorophenyl)alanine methyl ester (from Example A9 above) and allyl alcohol (Aldrich), the title compound was prepared as an oil. The reaction was monitored by silica gel tlc (Rf=0.62 in 25% EtOAc/hexanes). Purification was by preparative plate chromatography (silica gel using 25% EtOAc/hexanes as the eluant).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06667305B1 |
| Source dataset | uspto-grants-2003_12 |
| ORD ID | ord-8f10fe36e7814cbf831d18f836215f08 |
| Source note | uspto-grants-2003_12 |