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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 43351Generated: October 25, 2026

4-Cyanophenol → tert-Butyl 4-(4-cyanophenoxy)piperidine-1-carboxylate

https://huagongshe.com/reaction/43351

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-CyanophenolHCID 13019—
ReactantTert-butyl 4-hydroxypiperidine-1-carboxylateHCID 643502—
Producttert-Butyl 4-(4-cyanophenoxy)piperidine-1-carboxylateHCID 23019443—

Reaction Steps

The title compound was prepared from 4-hydroxybenzonitrile and 1,1-dimethylethyl 4-hydroxy-1-piperidinecarboxylate using a method similar to that described for D13.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08536182B2
Source datasetuspto-grants-2013_09
ORD IDord-bd52ff07ce2943018d46f87fab6db575
Source noteuspto-grants-2013_09