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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 433525Generated: October 26, 2026

o-Tolylacetic acid → 2-[(2-methylphenyl)acetamido]butyric Acid Iso-butyl Ester

https://huagongshe.com/reaction/433525

Reaction equation

Participants

RoleNameHCIDCharge
Reactanto-Tolylacetic acidHCID 69519—
ReactantIsobutyl 2-aminobutyrateHCID 13743360—
Product2-[(2-methylphenyl)acetamido]butyric Acid Iso-butyl EsterHCID 54573498—

Reaction Steps

Following General Procedure BI above and using 2-methylphenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06667305B1
Source datasetuspto-grants-2003_12
ORD IDord-e27395fa705f488a9a1125bc696c8e84
Source noteuspto-grants-2003_12