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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 433534Generated: October 30, 2026

3-(Methylthio)phenylacetic acid → N-[(3-methylthiophenyl)acetyl]alanine Iso-butyl Ester

https://huagongshe.com/reaction/433534

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Methylthio)phenylacetic acidHCID 2737461—
Reactant2-methylpropyl (2S)-2-aminopropanoateHCID 13743556—
ProductN-[(3-methylthiophenyl)acetyl]alanine Iso-butyl EsterHCID 15481777—

Reaction Steps

Following General Procedure BI above, and using 3-methylthiophenylacetic acid (CAS# 18698-73-2) and alanine iso-butyl ester (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06667305B1
Source datasetuspto-grants-2003_12
ORD IDord-099ca1db81bb4de18634f3edd061deab
Source noteuspto-grants-2003_12