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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 433538Generated: October 25, 2026

m-Tolylacetic acid → N-[(3-methylphenyl)acetyl]alanine Iso-butyl Ester

https://huagongshe.com/reaction/433538

Reaction equation

Participants

RoleNameHCIDCharge
Reactantm-Tolylacetic acidHCID 12121—
Reactant2-methylpropyl (2S)-2-aminopropanoateHCID 13743556—
ProductN-[(3-methylphenyl)acetyl]alanine Iso-butyl EsterHCID 53803690—

Reaction Steps

Following General Procedure BI above, and using 3-methylphenylacetic acid (Aldrich) and alanine iso-Butyl Ester (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06667305B1
Source datasetuspto-grants-2003_12
ORD IDord-5a953ce2919e434495176347bbcd4f5c
Source noteuspto-grants-2003_12