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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 433542Generated: October 26, 2026

p-Tolylacetic acid → N-[(4-methylphenyl)acetyl]alanine iso-butyl ester

https://huagongshe.com/reaction/433542

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Tolylacetic acidHCID 248474—
Reactant2-methylpropyl (2S)-2-aminopropanoateHCID 13743556—
ProductN-[(4-methylphenyl)acetyl]alanine iso-butyl esterHCID 53936136—

Reaction Steps

Following General Procedure BI above, and using 4-methylphenylacetic acid (Aldrich) and L-alanine iso-butyl ester (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06667305B1
Source datasetuspto-grants-2003_12
ORD IDord-5cd9e253c3274a13ab58066e58329769
Source noteuspto-grants-2003_12