反应详情

Following General Procedure BG and using 3,5-difluorophenylacetic acid (Aldrich) and alanine ethyl ester (Aldrich), the title compound was prepared as a solid with a melting point of 93°-95° C. The reaction was monitored by tlc on silica gel (Rf=0.8 in EtOAC) and purification was by chromatography on silica gel using EtOAc as the eluant followed by recrystallization from 1-chlorobutane.

1. customThe reaction was monitored by tlc on silica gel (Rf=0.8 in EtOAC) and purification
2. customfollowed by recrystallization from 1-chlorobutane