HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-Chloro-3-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane → 3-(4-Chloro-3-trifluoromethyl-phenyl)-5-(2-methyl-imidazol-1-yl-methyl)-pyridine Hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-Chloro-3-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | HCID 17750238 | — |
| Reactant | 3-Bromo-5-(2-methyl-imidazol-1-ylmethyl)-pyridine | HCID 23444965 | — |
| Product | 3-(4-Chloro-3-trifluoromethyl-phenyl)-5-(2-methyl-imidazol-1-yl-methyl)-pyridine Hydrochloride | HCID 23445051 | — |
Reaction Steps
The title compound, MS: m/e=352.3 (M+H+) was obtained as a beige foam (49% yield) by the reaction of 3-bromo-5-(2-methyl-imidazol-1-yl-methyl)-pyridine with 2-(4-chloro-3-trifluoromethyl-phenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06667335B2 |
| Source dataset | uspto-grants-2003_12 |
| ORD ID | ord-cdbd6d5f8ffc409caf3c3c3080f91eb8 |
| Source note | uspto-grants-2003_12 |