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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 433603Generated: October 25, 2026

Methyl 2-iodoisonicotinate → 2-(3,4-Dichloro-phenyl)-isonicotinic acid methyl ester

https://huagongshe.com/reaction/433603

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-iodoisonicotinateHCID 196869—
Reactant3,4-Dichlorobenzeneboronic acidHCID 2734330—
Product2-(3,4-Dichloro-phenyl)-isonicotinic acid methyl esterHCID 69040624—

Reaction Steps

The title compound, MS: m/e=281.0 (M+) was obtained as a light brown solid (59% yield) by the reaction of 2-iodo-isonicotinic acid methyl ester with 3,4-dichlorophenyl boronic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06667335B2
Source datasetuspto-grants-2003_12
ORD IDord-299fae61360646ddaeed1ff4fe734288
Source noteuspto-grants-2003_12