HRID433788

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID10820784

未命名化合物

结构：COC(=O)[C@@H](NC(=O)Oc1ccc([N+](=O)[O-])cc1)C(C)C

HCID15344176

Methyl N-[(4-nitrophenoxy)carbonyl]-L-valinate

C13H16N2O6

结构：COC(=O)[C@H](C)NC(=O)Oc1ccc([N+](=O)[O-])cc1

HCID54298210

未命名化合物

PRODUCTS

生成物

结构：COC(=O)[C@H](C)NC(=O)N(C)Cc1coc(C(C)C)n1

HCID10708114

未命名化合物

收率 66%

PROCEDURE

实验过程

Using the procedure of Example 1S, but replacing 2-isopropyl-4-(((N-methyl)amino)methyl)thiazole with 2-isopropyl-4-(((N-methyl)amino)methyl)-oxazole and relacing N-(((4-nitrophenyl)oxy)carbonyl)-L-valine methyl ester with N-(((4-nitrophenyl)oxy)carbonyl)-L-alanine methyl ester provided the desired compound in 66% yield. 1H NMR (CDCl3) δ 1.32 (d, 6H), 1.42 (d, 3H), 2.96 (s, 3H), 3.05 (m, 1H), 3.75 (s, 3H), 4.30 (s, 2H), 4.47 (m, 1H), 5.80 (br d, 1H), 7.46 (s, 1H). Mass spectrum: (M+H)+=284.