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HRID433877

反应详情

EQUATION

反应方程式

HRID 433877 的结构方程式

REACTANTS

反应物

2
结构：[BH4-].[Na+]
HCID4311764

Sodium borohydride (Na(BH4))

H4BNa

结构：C=C1C[C@]2(C)C(=O)CC[C@H]2[C@@H]2[C@H](C)Cc3cc(OC)ccc3[C@@H]12
HCID15549875

未命名化合物

PRODUCTS

生成物

1
结构：C=C1C[C@]2(C)[C@@H](O)CC[C@H]2[C@H]2[C@H]1[C@H]1CCC(=O)C=C1C[C@H]2C
HCID57098977

未命名化合物

PROCEDURE

实验过程

3-Methoxy-7α-methyl-11-methyleneestr-1,3,5(10)-trien-17-one (A-11) was subjected to sodium borohydride reduction of the 17-ketone function, Birch reduction with lithium/NH3(1), and acid hydrolysis and rearrangement to the title compound. Experimental details are as follows: