反应详情

To a solution of 60 ml of acetic acid and 43 ml of acetic anhydride at 0° C., was added slowly 40 g (0.27 mol) of acetonedicarboxylic acid. The mixture was stirred and the temperature was not allowed to rise above 10° C. The acid was dissolved slowly and a pale yellow precipitate formed. After 3 h the product was filtered, washed with 30 ml of glacial acetic acid and 100 ml of benzene. The white powder obtained was dried at high vacuum to afford 30 g of acetonedicarboxylic acid anhydride (yield 86%). Mp 137-138° C.

1. customto rise above 10° C
2. dissolutionThe acid was dissolved slowly
3. customa pale yellow precipitate formed
4. filtrationAfter 3 h the product was filtered
5. washwashed with 30 ml of glacial acetic acid and 100 ml of benzene
6. customThe white powder obtained
7. customwas dried at high vacuum