HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → N-[(2,6-difluorophenyl)methylidene]hydroxylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 2,6-Difluorobenzaldehyde | HCID 136284 | — |
| Reactant | Hydroxyamine hydrochloride | HCID 443297 | — |
| Solvent | Water | HCID 962 | — |
| Product | N-[(2,6-difluorophenyl)methylidene]hydroxylamine | HCID 698216 | 110.3% |
Reaction Steps
In a fashion similar to that for preparation 13, 2,6-difluorobenzaldehyde (5.00 g, 35.2 mmol), hydroxylamine hydrochloride (2.93 g, 29.6 mmol), NaOH (7.04 g in 7.0 ml of water), ethanol (15 ml), water (15 ml), and ice (30 g) afforded 2,6-difluorobenzaldehyde oxime (5.13 g, 93%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06670373B1 |
| Source dataset | uspto-grants-2003_12 |
| ORD ID | ord-eb167c0a7f7d43698e1aa65b13254010 |
| Source note | uspto-grants-2003_12 |