HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorosuccinimide → 2,6-Difluorobenzoyl chloride oxime
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorosuccinimide | HCID 31398 | — |
| Reactant | N-[(2,6-difluorophenyl)methylidene]hydroxylamine | HCID 698216 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2,6-Difluorobenzoyl chloride oxime | HCID 53395382 | 65% |
Reaction Steps
In a fashion similar to that for preparation 14, 2,6-difluorobenzaldehyde oxime (2.00 g, 12.7 mmol), N-chlorosuccinimide (1.75 g, 13.2 mmol), and DMF (20 ml) gave 2,6-difluorobenzoylchloride oxime (1.58 g, 65%) after column chromatography (silica gel, hexanes/diethyl ether gradient).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06670373B1 |
| Source dataset | uspto-grants-2003_12 |
| ORD ID | ord-5db88d7579b64a6295ccac388dc398f8 |
| Source note | uspto-grants-2003_12 |