Ethyl 3-bromopropionate → HCID 54696993, compound

HRID 434095Notes

Reaction equation

HRID 434095 reaction equation
[CH2:1]([O:5][C:6]1[C:7](=[O:18])[O:8][C:9]2[CH:16]=[C:15]([OH:17])[CH:14]=[CH:13][C:10]=2[C:11]=1[OH:12])[CH2:2][CH2:3][CH3:4].Br[CH2:20][CH2:21][C:22]([O:24][CH2:25][CH3:26])=[O:23]>>[CH2:1]([O:5][C:6]1[C:7](=[O:18])[O:8][C:9]2[CH:16]=[C:15]([O:17][CH2:20][CH2:21][C:22]([O:24][CH2:25][CH3:26])=[O:23])[CH:14]=[CH:13][C:10]=2[C:11]=1[OH:12])[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 68320Ethyl 3-bromopropionateHCID 54696750HCID 54696750, compound

Product 1

HCID 54696993HCID 54696993, compound

Procedure

In the same manner as in Reference Example 3, except that an equimolar amount of 3-butoxy-4,7-dihydroxy-2H-1-benzopyran-2-one was used in place of 3-hexyloxy-4,5-dihydroxy-2H-1-benzopyran-2-one, and ethyl 3-bromopropionate was used in place of ethyl bromoacetate in Reference Example 3, 3-butoxy-4-hydroxy-7-(2-ethoxycarbonylethoxy)-2H-1-benzopyran-2-one was obtained.

Sources & evidence

ORD record
ord-7a47233506b547fd80296b9b8f862102
Source dataset
uspto-grants-2003_12
Patent number
US06670391B2

Reaction notes

Loading…