Ethyl 3-bromopropionate → HCID 54696887, compound

HRID 434097Notes

Reaction equation

HRID 434097 reaction equation
[CH2:1]([O:9][C:10]1[C:11](=[O:22])[O:12][C:13]2[CH:20]=[C:19]([OH:21])[CH:18]=[CH:17][C:14]=2[C:15]=1[OH:16])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].Br[CH2:24][CH2:25][C:26]([O:28][CH2:29][CH3:30])=[O:27]>>[CH2:1]([O:9][C:10]1[C:11](=[O:22])[O:12][C:13]2[CH:20]=[C:19]([O:21][CH2:24][CH2:25][C:26]([O:28][CH2:29][CH3:30])=[O:27])[CH:18]=[CH:17][C:14]=2[C:15]=1[OH:16])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

Participants

3

Reactant 2

HCID 68320Ethyl 3-bromopropionateHCID 54696943HCID 54696943, compound

Product 1

HCID 54696887HCID 54696887, compound

Procedure

In the same manner as in Reference Example 3, except that an equimolar amount of 3-octyloxy-4,7-dihydroxy-2H-1-benzopyran-2-one was used in place of 3-hexyloxy-4,5-dihydroxy-2H-1-benzopyran-2-one, and ethyl 3-bromopropionate was used in place of ethyl bromoacetate in Reference Example 3, 3-octyloxy-4-hydroxy-7-(2-ethoxycarbonylethoxy)-2H-1-benzopyran-2-one was obtained.

Sources & evidence

ORD record
ord-9834b890097a44c384f8dc34691d6571
Source dataset
uspto-grants-2003_12
Patent number
US06670391B2

Reaction notes

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