Ethyl 3-bromopentanoate → 3-hexyloxy-4-hydroxy-8-(4-ethoxycarbonylbutoxy)-2H-1-benzopyran-2-one

HRID 434107Notes

Reaction equation

HRID 434107 reaction equation
[CH2:1]([O:7][C:8]1[C:9](=[O:20])[O:10][C:11]2[C:18]([OH:19])=[CH:17][CH:16]=[CH:15][C:12]=2[C:13]=1[OH:14])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].Br[CH:22]([CH2:29][CH3:30])[CH2:23][C:24]([O:26][CH2:27][CH3:28])=[O:25]>>[CH2:1]([O:7][C:8]1[C:9](=[O:20])[O:10][C:11]2[C:18]([O:19][CH2:30][CH2:29][CH2:22][CH2:23][C:24]([O:26][CH2:27][CH3:28])=[O:25])=[CH:17][CH:16]=[CH:15][C:12]=2[C:13]=1[OH:14])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6]

Participants

3

Reactant 2

HCID 18756570Ethyl 3-bromopentanoateHCID 54696930HCID 54696930, compound

Product 1

HCID 546968223-hexyloxy-4-hydroxy-8-(4-ethoxycarbonylbutoxy)-2H-1-benzopyran-2-one

Procedure

In the same manner as in Reference Example 3, except that an equimolar amount of 3-hexyloxy-4,8-dihydroxy-2H-1-benzopyran-2-one was used in place of 3-hexyloxy-4,5-dihydroxy-2H-1-benzopyran-2-one, and ethyl 3-bromopentanoate was used in place of ethyl bromoacetate in Reference Example 3, 3-hexyloxy-4-hydroxy-8-(4-ethoxycarbonylbutoxy)-2H-1-benzopyran-2-one was obtained.

Sources & evidence

ORD record
ord-83e9aff7bd4244b197d23f30ea7b03f2
Source dataset
uspto-grants-2003_12
Patent number
US06670391B2

Reaction notes

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