Nicotinic Acid → Magnesium nicotinate

HRID 434189Notes

Reaction equation

HRID 434189 reaction equation
[O-2].[Mg+2:2].[C:3]([OH:11])(=[O:10])[C:4]1[CH:9]=[CH:8][CH:7]=[N:6][CH:5]=1>C(O)C>[C:3]([O-:11])(=[O:10])[C:4]1[CH:9]=[CH:8][CH:7]=[N:6][CH:5]=1.[Mg+2:2].[C:3]([O-:11])(=[O:10])[C:4]1[CH:9]=[CH:8][CH:7]=[N:6][CH:5]=1

Participants

4

Reactant 2

HCID 938Nicotinic AcidHCID 6850729Magnesium monoxide

Product 1

HCID 23472Magnesium nicotinateYield 98.9%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

8 grams (0.2 Mole) of magnesium oxide, 49.2 grams (0.4 Mole) of nicotinic acid and 150 ml ethanol were placed into a beaker provided with a reflux condenser. The mixture was stirred and boiled at atmospheric pressure for 2 hours. The mixture was cooled and thereafter filtered yielding 53.1 grams of magnesium nicotinate in the form of a fine white powder.

Workup

  1. customprovided with a reflux condenser
  2. temperatureThe mixture was cooled
  3. filtrationfiltered

Sources & evidence

ORD record
ord-f36ec40277f24621ab9cc3f0b8c683cc
Source dataset
uspto-grants-2003_12
Patent number
US06670494B1

Reaction notes

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