Water → HCID 12095193, compound

Participants

Reaction Steps

To a solution of bis(2,6-dimethoxyphenyl)methanol (4.37 g, 0.014 mol) in acetonitrile (50 mL) and tetrahydrofuran (65 mL) was added p-toluenesulfonic acid monohydrate (2.73 g, 0.014 mol) at 0° C. The resulting solution was warmed to room temperature and stirred for 17 hours, after which water (60 mL) was added and the solvent removed under reduced pressure. The residue was extracted with diethyl ether and the combined extracts dried over anhydrous magnesium sulfate. Removal of the solvent in vacuo gave bis(2,6-dimethoxyphenyl)methane.

Provenance & Evidence