Sodium Hydroxide → HCID 13188845, compound

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Reaction Steps

Dissolve 90 mg of this ester in 0.5 ml ethanol and add 1 ml 1.0 N NaOH. Stir the mixture at room temperature for 3 hours, then dilute with water and extract with ether. Add solid sodium dihydrogen phosphate to the aqueous phase until it is acidic, then extract with ethyl acetate. Dry the ethyl acetate over Na2SO4, filter and concentrate to obtain 1-(1-carboxyethyl)perhydroazocin-2-one, m.p. 166-167 (from acetone-ether).

Provenance & Evidence