Sodium Hydroxide → HCID 20493326, compound

HRID 434340Notes

Reaction equation

HRID 434340 reaction equation
C([O:3][C:4]([CH:6]([N:8]1[CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][C:10](=[CH2:16])[C:9]1=[O:17])[CH3:7])=[O:5])C.[OH-].[Na+]>>[C:4]([CH:6]([N:8]1[CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][C:10](=[CH2:16])[C:9]1=[O:17])[CH3:7])([OH:5])=[O:3]

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 20493319HCID 20493319, compound

Product 1

HCID 20493326HCID 20493326, compound

Procedure

Hydrolyze 100 mg 1-(1-ethoxycarbonylethyl)-3-methyleneperhydroazocin-2-one, prepared in Example 1, with dilute sodium hydroxide. Carefully acidfy the hydrolysate to pH 2 and extract with ethyl acetate. Dry and concentrate to obtain 1-(1-carboxyethyl)-3-methyleneperhydroazocin-2-one.

Workup

  1. extractionextract with ethyl acetate
  2. customDry
  3. concentrationconcentrate

Sources & evidence

ORD record
ord-f8d42ee2204444f79b02981e7711632e
Source dataset
uspto-grants-1983_08
Patent number
US04396616

Reaction notes

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