Toluene → HCID 13188850, compound

HRID 434342Notes

Reaction equation

HRID 434342 reaction equation
[C:1]([CH:5]([N:7]1[CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][C:9](=[CH2:15])[C:8]1=[O:16])[CH3:6])([O:3][CH3:4])=[O:2].C1(C)C=CC=CC=1.[C:24]([OH:27])(=[S:26])[CH3:25]>>[C:1]([CH:5]([N:7]1[CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][CH:9]([CH2:15][S:26][C:24](=[O:27])[CH3:25])[C:8]1=[O:16])[CH3:6])([O:3][CH3:4])=[O:2]

Participants

4

Reactant 3

HCID 1140TolueneHCID 13188849HCID 13188849, compoundHCID 178418634HCID 178418634, compound

Product 1

HCID 13188850HCID 13188850, compound

Procedure

A solution of 50 mg of 1-(1-carbomethoxyethyl)-3-methyleneperhydroazocin-2-one in thioacetic acid (0.5 ml) is kept at room temperature for 18 hours. Toluene (5 ml) is added and the mixture is concentrated to dryness under reduced pressure. The product is purified by preparative tlc on silica gel (system 5% acetone in chloroform) to yield the title compound (62 mg) as a colorless oil.

Workup

  1. concentrationthe mixture is concentrated to dryness under reduced pressure
  2. customThe product is purified by preparative tlc on silica gel (system 5% acetone in chloroform)

Sources & evidence

ORD record
ord-0a4c5a0ad0014fdeb91b93bea53acb8e
Source dataset
uspto-grants-1983_08
Patent number
US04396616

Reaction notes

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