Sodium Hydroxide → 1-(4-Acetylphenyl) propan-2-ol

HRID 434373Notes

Reaction equation

HRID 434373 reaction equation
C([O:4][CH:5]([CH3:16])[CH2:6][C:7]1[CH:12]=[CH:11][C:10]([C:13](=[O:15])[CH3:14])=[CH:9][CH:8]=1)(=O)C.[OH-].[Na+]>>[C:13]([C:10]1[CH:11]=[CH:12][C:7]([CH2:6][CH:5]([OH:4])[CH3:16])=[CH:8][CH:9]=1)(=[O:15])[CH3:14]

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 204938272-Acetoxy-1-(4-acetylphenyl)propane

Product 1

HCID 225984461-(4-Acetylphenyl) propan-2-olYield 104.4%

Procedure

2-Acetoxy-1-(4-acetylphenyl) propane (4.5 g) was heated for 2 hours in refluxing 2 N sodium hydroxide solution. The mixture was allowed to cool and the product was extracted into ether. Evaporation of the dried (MgSO4) extracts gave an oil (3.8 g).

Workup

  1. temperatureto cool
  2. extractionthe product was extracted into ether
  3. customEvaporation of the
  4. dry with materialdried (MgSO4)

Sources & evidence

ORD record
ord-f3d02f20e0444b7eb09a5c9a270b63d0
Source dataset
uspto-grants-1983_08
Patent number
US04396627

Reaction notes

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