反应详情

Chromic acid solution (11.5 ml, made by adding sulphuric acid [7.3 ml] to sodium dichromate [10.0 g] in water [30 ml] and making up to 50 ml with water) was added to a vigorously stirred solution of 1-(4-acetylphenyl) propan-2-ol (3.8 g) in ether (50 ml) keeping between 25°-30°. The mixture was stirred at ambient temperature for 2 hours, the organic phase was separated, washed with sodium bicarbonate solution and with saturated sodium chloride solution. The dried (MgSO4) solution was evaporated and distilled (2.5 g). b.p. 122°-128°/0.1 mm.

1. customkeeping between 25°-30°
2. customthe organic phase was separated
3. washwashed with sodium bicarbonate solution and with saturated sodium chloride solution
4. dry with materialThe dried (MgSO4) solution
5. customwas evaporated
6. distillationdistilled (2.5 g)