HRID434382

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6666

1,5-Naphthalenedisulfonic acid

C10H8O6S2

HCID20493724

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)C(=O)C(Oc1cccc(Cl)n1)n1cncn1.O=S(=O)(O)c1cccc2c(S(=O)(=O)O)cccc12

HCID20493723

未命名化合物

收率 94%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID180

Acetone

C3H6O

2 次

PROCEDURE

实验过程

10 g (0.034 mol) of 1-(6-chloropyridin-2-yl-oxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)-butan-2-one (Example 1) were dissolved in 50 ml of acetone, and a solution of 8 g (0.027 mol) of naphthalene-1,5-disulphonic acid in 50 ml of acetone was added. The salt which precipitated after some time was filtered off and dried. 14 g (94% of theory) of 1-(6-chloropyridin-2-yl-oxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)-butan-2-one naphthalene-1,5-disulphonate of melting point 212°-215° C. (decomposition) were obtained.

WORKUP

后处理

customThe salt which precipitated after some time
filtrationwas filtered off
customdried

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-67881597b9c14b8e92c44f7668bfd60d
来源数据集: uspto-grants-1983_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04396624
来源说明: uspto-grants-1983_08

反应 SMILES

[Cl:1][C:2]1[N:7]=[C:6]([O:8][CH:9]([N:16]2[CH:20]=[N:19][CH:18]=[N:17]2)[C:10](=[O:15])[C:11]([CH3:14])([CH3:13])[CH3:12])[CH:5]=[CH:4][CH:3]=1.[C:21]1([S:35]([OH:38])(=[O:37])=[O:36])[C:30]2[CH:29]=[CH:28][CH:27]=[C:26]([S:31]([OH:34])(=[O:33])=[O:32])[C:25]=2[CH:24]=[CH:23][CH:22]=1>CC(C)=O>[C:21]1([S:35]([OH:38])(=[O:37])=[O:36])[C:30]2[CH:29]=[CH:28][CH:27]=[C:26]([S:31]([OH:34])(=[O:33])=[O:32])[C:25]=2[CH:24]=[CH:23][CH:22]=1.[Cl:1][C:2]1[N:7]=[C:6]([O:8][CH:9]([N:16]2[CH:20]=[N:19][CH:18]=[N:17]2)[C:10](=[O:15])[C:11]([CH3:12])([CH3:13])[CH3:14])[CH:5]=[CH:4][CH:3]=1