Succinic Acid → HCID 20471294, compound

HRID 434415Notes

Reaction equation

HRID 434415 reaction equation
[C:1]([OH:8])(=[O:7])[CH2:2][CH2:3][C:4]([OH:6])=[O:5].[CH3:9][C:10]1[CH:11]=[C:12]([CH:19]=[CH:20][C:21]=1[CH3:22])[CH2:13][N:14]1[CH:18]=[CH:17][N:16]=[CH:15]1>C(O)C>[C:1]([OH:8])(=[O:7])[CH2:2][CH2:3][C:4]([OH:6])=[O:5].[CH3:9][C:10]1[CH:11]=[C:12]([CH:19]=[CH:20][C:21]=1[CH3:22])[CH2:13][N:14]1[CH:18]=[CH:17][N:16]=[CH:15]1

Participants

4

Reactant 2

HCID 1110Succinic AcidHCID 130453671-[(3,4-Dimethylphenyl)methyl]-1H-imidazole

Product 1

HCID 20471294HCID 20471294, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

A hot solution of succinic acid (0.295 g, 0.0025 mol) in ethanol (20 ml) was added to a stirred, hot solution of 1-(3,4-dimethylbenzyl)imidazole (0.46 g, 0.0025 mol) in hot ethanol (10 ml). After boiling for 0.25 h, the solution was evaporated under reduced pressure to afford a white solid. Recrystallisation of the solid from ethyl acetate/petroleum ether (b.p. 40°-60°) afforded 1-(3,4-dimethylbenzyl)imidazole hydrogen succinate as white crystals, m.p. 134°-135°

Workup

  1. customthe solution was evaporated under reduced pressure
  2. customto afford a white solid
  3. customRecrystallisation of the solid from ethyl acetate/petroleum ether (b.p. 40°-60°)

Sources & evidence

ORD record
ord-083ce1bee30940418daf6762c8ce6adb
Source dataset
uspto-grants-1983_08
Patent number
US04396771

Reaction notes

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