Ethylene Glycol → HCID 13175521, compound

Participants

Reaction Conditions

Reaction Steps

N-(2,2-Diethoxyethyl)-N-propyl-2,6-dinitro-4-trifluoromethylaniline (5.5 grams; 0.0132 mol), ethylene glycol (0.84 grams; 0.0132 mole), p-toluenesulfonic acid (200 mg) and ethanol solvent were placed in a glass reaction flask equipped with stirrer, heating mantle and thermometer. The mixture was heated to 120° C. After the reaction was completed, the reaction mixture was cooled to room temperature, ethyl acetate was added and the mixture was washed with water and sodium bicarbonate solution. The solution was then dried over anhydrous magnesium sulfate and evaporated to yield the desired product N-propyl-N-1,3-dioxolan-2-ylmethyl-2,6-dinitro-4-trifluoromethylaniline as an oil.

Provenance & Evidence