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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 434478Generated: October 26, 2026

Gamma-Butyrolactone → 1-(3-Hydroxypropyl)pyrrolidin-2-one

https://huagongshe.com/reaction/434478

Reaction equation

Participants

RoleNameHCIDCharge
ReactantGamma-ButyrolactoneHCID 7302—
Reactant3-Amino-1-propanolHCID 9086—
Product1-(3-Hydroxypropyl)pyrrolidin-2-oneHCID 56674478.6%

Reaction Steps

3-aminopropanol reacted in similar manner to Example 2 with butyrolactone furnished a 78.6% yield of N-(3-hydroxypropyl)-2-pyrrolidinone, b.p. 160° C./3 torr.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04397750
Source datasetuspto-grants-1983_08
ORD IDord-3e1a5ff4ce164c42a7adb84af9fec025
Source noteuspto-grants-1983_08