Phenyl isocyanate → N-Benzyl-N-butyl-N'-phenylurea

HRID 434531Notes

Reaction equation

HRID 434531 reaction equation
[C:1]1([N:7]=[C:8]=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:10]([NH:17][CH2:18][CH2:19][CH2:20][CH3:21])[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>CCCCCC>[CH2:10]([N:17]([CH2:18][CH2:19][CH2:20][CH3:21])[C:8]([NH:7][C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)=[O:9])[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Participants

4

Reactant 2

HCID 7672Phenyl isocyanateHCID 75467Benzenemethanamine, N-butyl-

Product 1

HCID 307352N-Benzyl-N-butyl-N'-phenylurea

Reagents, catalysts & solvents 1

HCID 8058HexaneSolvent2×

Procedure

A solution of 4.89 g. of phenylisocyanate in 100 ml. of hexane was added to a solution of 4.41 g. of N-benzyl-n-butylamine in 150 ml. of hexane and the solution was stirred at room temperature for 2 hours and then evaporated. The residual solid was recrystallized from pentane to yield 1-benzyl-1-(n-butyl)-3-(phenyl)urea.

Workup

  1. customevaporated
  2. customThe residual solid was recrystallized from pentane

Sources & evidence

ORD record
ord-6dcd3ff37c3344f595cd38405c9399b5
Source dataset
uspto-grants-1983_08
Patent number
US04397868

Reaction notes

Loading…