N-bromobutanimide → HCID 68405898, compound

HRID 43455Notes

Reaction equation

HRID 43455 reaction equation
[CH3:1][C:2]1[NH:6][C:5]([C:7]([O:9][CH2:10][CH3:11])=[O:8])=[N:4][CH:3]=1.C1C(=O)N([Br:19])C(=O)C1>>[Br:19][C:3]1[N:4]=[C:5]([C:7]([O:9][CH2:10][CH3:11])=[O:8])[NH:6][C:2]=1[CH3:1]

Participants

3

Reactant 2

HCID 67184N-bromobutanimideHCID 24974466Ethyl 5-methyl-1H-imidazole-2-carboxylate2×

Product 1

HCID 68405898HCID 68405898, compoundYield 94%

Procedure

The same operation as in Example (1c) was performed using ethyl 5-methyl-1H-imidazole-2-carboxylate obtained by the method described in Example (5a) (0.30 g, 1.95 mmol) and NBS (0.35 g, 1.96 mmol), to obtain 0.43 g of the title compound as a white solid (94%).

Workup

  1. customobtained by the method

Sources & evidence

ORD record
ord-d693ef5b612a4617add9d3780e2fbc6a
Source dataset
uspto-grants-2013_09
Patent number
US08536197B2

Reaction notes

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