HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiourea → Ethyl 2-(2-aminothiazol-4-yl)-2-n-butoxyiminoacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiourea | HCID 2723790 | — |
| Reactant | Ethyl 4-bromo-2-n-butoxyimino-acetoacetate | HCID 53744206 | — |
| Product | Ethyl 2-(2-aminothiazol-4-yl)-2-n-butoxyiminoacetate | HCID 54097425 | 40.5% |
Reaction Steps
93 g (0.32 mole) of ethyl 4-bromo-2-n-butoxyimino-acetoacetate and 24 g (0.32 mole) of thiourea undergo a condensation reaction analogously to Example 4, stage 3, to give 35.2 g of ethyl 2-(2-aminothiazol-4-yl)-2-n-butoxyimino-acetate of melting point 129.5°-131°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04399131 |
| Source dataset | uspto-grants-1983_08 |
| ORD ID | ord-9eafcaa0327a42dcbd5209c47cd407e5 |
| Source note | uspto-grants-1983_08 |