Trityl chloride → 2-n-Butoxyimino-2-(2-tritylaminothiazol-4-yl)-acetic acid

Participants

Reaction Steps

Stages 4 and 5: 35.2 g (0.13 mole) of ethyl 2-(2-aminothiazol-4-yl)-2-n-butoxyimino-acetate are tritylated with 44.6 g (0.155 mole) of trityl chloride (97% pure) analogously to Example 4, stage 4, and the product is split, without further purification, as described in Example 4, stage 5, to give 37 g of 2-n-butoxyimino-2-(2-tritylaminothiazol-4-yl)-acetic acid.

Provenance & Evidence