HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorosuccinimide → Ethyl 4-chloro-5-isopropyl-1h-imidazole-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorosuccinimide | HCID 31398 | — |
| Reactant | Ethyl 5-isopropyl-1H-imidazole-2-carboxylate | HCID 68406002 | — |
| Product | Ethyl 4-chloro-5-isopropyl-1h-imidazole-2-carboxylate | HCID 67548351 | 77% |
Reaction Steps
The same operation as in Example (1c) was performed using ethyl 5-(propan-2-yl)-1H-imidazole-2-carboxylate obtained in Example (35d) (0.82 g, 4.50 mmol) and NCS (0.60 g, 4.51 mmol), to obtain 0.75 g of the title compound as a white solid (77%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08536197B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-4002071e8400466e8434fbd6ae792f68 |
| Source note | uspto-grants-2013_09 |