HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(dimethoxymethyl)-5-ethyl-4-(trifluoromethyl)-1H-imidazole → 5-Ethyl-4-(trifluoromethyl)-1H-imidazole-2-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(dimethoxymethyl)-5-ethyl-4-(trifluoromethyl)-1H-imidazole | HCID 68406043 | — |
| Solvent | Sulfuric Acid | HCID 1118 | — |
| Product | 5-Ethyl-4-(trifluoromethyl)-1H-imidazole-2-carbaldehyde | HCID 86648487 | 29.1% |
Reaction Steps
The same operation as in Example (33b) was performed using 2-(dimethoxymethyl)-5-ethyl-4-(trifluoromethyl)-1H-imidazole obtained in Example (39c) (about 4.09 mmol) and 2 N sulfuric acid (30 mL), to obtain 228.3 mg of the title compound as a white solid (29%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08536197B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-c2732bdc31d840f1a6f62f8d8476e4c5 |
| Source note | uspto-grants-2013_09 |