HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl cis(+/-)-3-(4-{[(benzyloxy)carbonyl]amino}-3-methoxypiperidin-1-yl)benzoate → tert-Butyl cis(+/-)-3-(4-amino-3-methoxypiperidin-1-yl)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl cis(+/-)-3-(4-{[(benzyloxy)carbonyl]amino}-3-methoxypiperidin-1-yl)benzoate | HCID 86648497 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Product | tert-Butyl cis(+/-)-3-(4-amino-3-methoxypiperidin-1-yl)benzoate | HCID 86648499 | — |
Reaction Steps
The same operation as in Example (40e) was performed using tert-butyl cis(±)-3-(4-{[(benzyloxy)carbonyl]amino}-3-methoxypiperidin-1-yl)benzoate obtained in Example (42c) (115 mg, 0.26 mmol) and a 10% palladium-carbon catalyst (40 mg), to obtain the title compound. The resulting compound was used for the next reaction without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08536197B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-ae6c3392537c4496afe33f4aef99babf |
| Source note | uspto-grants-2013_09 |