HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorosuccinimide → ethyl 4-chloro-5-propyl-1H-imidazole-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorosuccinimide | HCID 31398 | — |
| Reactant | ethyl 5-propyl-1H-imidazole-2-carboxylate | HCID 14990234 | — |
| Product | ethyl 4-chloro-5-propyl-1H-imidazole-2-carboxylate | HCID 67548193 | 73.5% |
Reaction Steps
The same operation as in Example (1c) was performed using ethyl 5-propyl-1H-imidazole-2-carboxylate obtained in Example (46b) (1.01 g, 5.54 mmol) and NCS (0.74 g, 5.50 mmol), to obtain 876 mg of the title compound as a white solid (73%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08536197B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-b4e4daa318bf445eb089adbc4eb6aea1 |
| Source note | uspto-grants-2013_09 |