HCID 178418546, compound → HCID 178447862, compound

HRID 435097Notes

Reaction equation

HRID 435097 reaction equation
[CH2:1]([C@H:4]1[CH2:9][CH2:8][C@H:7]([C:10]2[CH:15]=[CH:14][C:13]([CH2:16][CH2:17][C:18]3[CH:23]=[CH:22][C:21](Br)=[CH:20][CH:19]=3)=[CH:12][CH:11]=2)[CH2:6][CH2:5]1)[CH2:2][CH3:3].[Cu][C:26]#[N:27]>N1C=CC=CC=1.CN1CCCC1=O>[CH2:1]([C@H:4]1[CH2:9][CH2:8][C@H:7]([C:10]2[CH:15]=[CH:14][C:13]([CH2:16][CH2:17][C:18]3[CH:23]=[CH:22][C:21]([C:26]#[N:27])=[CH:20][CH:19]=3)=[CH:12][CH:11]=2)[CH2:6][CH2:5]1)[CH2:2][CH3:3]

Participants

4

Reactant 2

HCID 178418546HCID 178418546, compoundHCID 178447861HCID 178447861, compound

Product 1

HCID 178447862HCID 178447862, compound

Reagents, catalysts & solvents 1

HCID 19599106HCID 19599106, compoundSolvent

Procedure

Analogously to Example 4(b), 1-[4-(trans-4-n-propylcyclohexyl)-phenyl]-2-(4-bromophenyl)-ethane is reacted with copper(I) cyanide in pyridine/N-methylpyrrolidone to give 1-[4-(trans-4-n-propylcyclohexyl)-phenyl]-2-(4-cyanophenyl)-ethane; m.p. 36°.

Sources & evidence

ORD record
ord-af779975bbde425fb91b21e5dd46e3e7
Source dataset
uspto-grants-1983_08
Patent number
US04400293

Reaction notes

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