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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 435218Generated: October 25, 2026

O-Cresol → 2,6-Dimethylphenol

https://huagongshe.com/reaction/435218

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-CresolHCID 335—
ReactantPhenolHCID 996—
ReactantDimethyl EtherHCID 8254—
ReactantSilicon oxide (SiO)HCID 66241—
ReactantBarium Oxide Nanoparticle DispersionHCID 9855530—
CatalystFerrous oxideHCID 449809—
CatalystHCID 178419084HCID 178419084—
SolventWaterHCID 962—
Product2,6-DimethylphenolHCID 11335—

Reaction Steps

A mixture of o-cresol and phenol, dimethyl ether and water in a molar ratio of 1:2:2.6 were reacted as described in Example 1. The catalyst contained iron oxide, vanadium oxide, silicon oxide and barium oxide in a molar ratio of 100:2:10:0.1. After working up, 2.6-xylenol was obtained with a selectivity of 99%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04400557
Source datasetuspto-grants-1983_08
ORD IDord-0e577805cbc34edb9d3509a4195c1f30
Source noteuspto-grants-1983_08