HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → 2-(2-Formamidothiazol-4-yl)-2-isopropoxyiminoacetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 2-Isopropoxyimino-2-(2-aminothiazol-4-yl)acetic acid | HCID 54100055 | — |
| Solvent | Formic Acid | HCID 284 | — |
| Product | 2-(2-Formamidothiazol-4-yl)-2-isopropoxyiminoacetic acid | HCID 53809275 | 83.5% |
Reaction Steps
2-(2-Aminothiazol-4-yl)-2-iso-propoxyiminoacetic acid (syn isomer, 4 g.), acetic anhydride (7.6 g. ) and formic acid (3.4 g.) were treated in a similar manner to that of Example F-(5) to give 2-(2-formamidothiazol-4-yl)-2-iso-propoxyiminoacetic acid (syn isomer, 3.75 g.), mp. 168° to 169° C. (dec.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04400379 |
| Source dataset | uspto-grants-1983_08 |
| ORD ID | ord-404f47ebbb274bb6846ad29c703090fd |
| Source note | uspto-grants-1983_08 |