HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → HCID 86648548, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | Ethyl 2-bromobenzo[d]thiazole-7-carboxylate | HCID 67073467 | — |
| Reactant | HCID 86648549 | HCID 86648549 | — |
| Product | HCID 86648548 | HCID 86648548 | 65% |
Reaction Steps
The same operation as in Example (1h) was performed using tert-butyl cis(±)-3-(butylamino)-4-{[(4-chloro-5-ethyl-1H-imidazol-2-yl)carbonyl]amino}piperidine-1-carboxylate obtained by the method described in Example (77d) (12.3 mg, 0.029 mmol), sodium carbonate (45 mg, 0.42 mmol) and ethyl 2-bromo-1,3-benzothiazole-7-carboxylate obtained in Example (1f) (10.4 mg, 0.036 mmol), to obtain 10.0 mg of the title compound (65%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08536197B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-27557212c3e748fab405e1dc5078671d |
| Source note | uspto-grants-2013_09 |