Hydrazine hydrate (1:1) → HCID 178445947, compound

Participants

Reaction Steps

The substance [45] (67.22 g, 90 mM) was dissolved in DMF (300 ml), hydrazine hydrate (45.6 ml, 0.95 M) was added, and the mixture was stirred at room temperature overnight. The DMF was removed in vacuo and the residue was dissolved in ethyl acetate (800 ml). This solution was washed with water, dehydrated with anhydrous sodium sulfate and concentrated in vacuo to obtain the powdered substance [46] (55 g, yield: 91.1%).

Provenance & Evidence