HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → Methyl 5-chloro-4-methyl-5-oxopentanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 4-Carbomethoxy-2-methylbutanoic acid | HCID 13192897 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Methyl 5-chloro-4-methyl-5-oxopentanoate | HCID 13192898 | — |
Reaction Steps
The starting material is prepared as follows: 9.64 g of oxalyl chloride are added to the solution of 6.1 g of 4-carbomethoxy-2-methylbutanoic acid (U.S. Pat. No. 4,052,511) in 50 ml of methylene chloride. The mixture is refluxed for two hours and evaporated, to yield the 4-carbomethoxy-2-methylbutanoyl chloride, which is used as such without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04401818 |
| Source dataset | uspto-grants-1983_08 |
| ORD ID | ord-da472c73cc0146febef864ca383b9c23 |
| Source note | uspto-grants-1983_08 |