Dl-Phenylalanine → HCID 131713065, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 6 g of L-phenylalanine p-xylenesulfonate, 60 ml of 97% formic acid, 0.85 g of DL-phenylalanine (0.3 mole per mole of L-phenylalanine p-xylenesulfonate) and 0.36 ml of salicylaldehyde (0.2 mole per mole of L-phenylalanine p-xylenesulfonate) were stirred at 100° C. for 4 hours. After the reaction, 1.14 g of p-xylenesulfonic acid dihydrate was dissolved in the mixture, and said mixture was condensed to dryness. 40 ml of acetone were added to the mixture, and said mixture was ice-cooled. The crystalline precipitates were collected by filtration, whereby 6.64 g of DL-phenylalanine p-xylenesulfonate were obtained.

Provenance & Evidence