Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
O-Cresol → alpha-Hydroxy-beta-(2-Methylphenoxy)-N-(1-Methylethyl)Benzenepropanamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | O-Cresol | HCID 335 | — |
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | 18-Crown-6 | HCID 28557 | — |
| 반응물 | N-(1-methylethyl)-3-phenyl-2-oxiranecarboxamide | HCID 13041334 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | alpha-Hydroxy-beta-(2-Methylphenoxy)-N-(1-Methylethyl)Benzenepropanamide | HCID 13041342 | — |
반응 단계
This compound was prepared from N-(1-methylethyl)-3-phenyl-2-oxiranecarboxamide (8.2 g.) o-cresol (4.3 g.), sodium hydride (50% oil dispersion, 1.9 g.), 18-crown-6 (1.0 g.), and acetonitrile (250 ml.) as described in Example 12. The compound after recrystallization from ether melted at 123°-124°, and weighed 1.25 g.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04401832 |
| 출처 데이터셋 | uspto-grants-1983_08 |
| ORD ID | ord-a1bb3436e102452e9c45818abfd6b1f7 |
| 출처 메모 | uspto-grants-1983_08 |