HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl bromoacetate → 3-Bromo-2-methoxyphenoxyacetic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl bromoacetate | HCID 60984 | — |
| Reactant | 3-Bromo-2-methoxyphenol | HCID 21877534 | — |
| Product | 3-Bromo-2-methoxyphenoxyacetic acid methyl ester | HCID 54183204 | — |
Reaction Steps
The compound of Formula XVIII wherein s is zero can also be prepared by treating 3-bromo-2-methoxyphenol with methyl bromoacetate to give 3-bromo-2-methoxyphenoxyacetic acid methyl ester which is reduced to the alcohol using, e.g., diisobutylaluminum hydride with subsequent protection of the alcohol with an R12 protecting group as generally described hereinbefore.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04401824 |
| Source dataset | uspto-grants-1983_08 |
| ORD ID | ord-992ba6eabc2d43408cdc5486d3186ed8 |
| Source note | uspto-grants-1983_08 |