Ethanol → HCID 70638487, compound

HRID 435575Notes

Reaction equation

HRID 435575 reaction equation
[I-:1].[CH3:2][NH+:3]1[CH:7]=[CH:6][N:5]([CH3:8])[CH:4]1[CH3:9].[S:10]1[CH:14]=[CH:13][CH:12]=[C:11]1[CH:15]=O.C(O)C.[OH-].[K+]>O>[I-:1].[CH3:2][NH+:3]1[CH:7]=[CH:6][N:5]([CH3:8])[CH:4]1[CH:9]=[CH:15][C:11]1[S:10][CH:14]=[CH:13][CH:12]=1

Participants

6

Reactant 4

HCID 702EthanolHCID 73642-ThiophenecarboxaldehydeHCID 14797Potassium HydroxideHCID 70639049HCID 70639049, compound

Product 1

HCID 70638487HCID 70638487, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 5.0 g of 1,2,3-trimethyl-1H-imidazolium iodide, 2ml of 2-thiophenecarboxaldehyde, 20 ml of absolute ethanol and 1 g of potassium hydroxide is refluxed for 25 minutes. Water is added to the cooled mixture and the resulting solid is filtered off. Recrystallization from ethanol yields 3.8 g of the title compound, melting point 309°-311° C.

Workup

  1. temperatureis refluxed for 25 minutes
  2. filtrationthe resulting solid is filtered off
  3. customRecrystallization from ethanol

Sources & evidence

ORD record
ord-18dbdf66e7a94389ac4c8c24b6faed45
Source dataset
uspto-grants-1977_02
Patent number
US04006137

Reaction notes

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