[5-Nitro-2-(phenylsulfanyl)phenyl]acetic acid → HCID 12362917, compound

Participants

Reaction Steps

78.4 g of 3-nitro-6-(phenylthio)-phenylacetic acid and 400 g of polyphosphoric acid are held at 105° - 110° C for 90 minutes with stirring. The mixture is subsequently diluted with ice and water and extracted with benzene. The organic phase is washed successively with water and aqueous sodium bicarbonate solution, dried over magnesium sulphate and evaporated under reduced pressure. There is obtained 10,11 -dihydro- 2-nitro-dibenzo[b,f]thiepin-10-one of melting point 171° - 172° C.

Provenance & Evidence