Sulfuric Acid → HCID 12362918, compound

Participants

Reaction Steps

165.3 g of 10,11-dihydro-2-nitro-dibenzo[b,f]thiepin- 10-one are suspended in 6 litres of dioxane and treated with a solution of 63 g of sodium borohydride in 300 ml of dioxane and 300 ml of water. The mixture is stirred overnight at room temperature, then diluted with water, made neutral with sulphuric acid and extracted with ethyl acetate. The organic phase is washed with water, dried over sodium sulphate and evaporated under reduced pressure. The 10,11-dihydro-2-nitro- dibenzo[b,f]thiepin-10-ol obtained is recrystallised from ethyl acetate; melting point 144° - 146° C.

Provenance & Evidence