HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 12232362, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | HCID 12232357 | HCID 12232357 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 12232362 | HCID 12232362 | — |
Reaction Steps
22 g of 2-fluoro-10,11-dihydro-dibenzo[b,f]thiepin-10-one are suspended in 110 ml of ethanol and treated with 6.1 g of sodium borohydride. The mixture is heated under reflux for 10-15 minutes, then treated with water and extracted with chloroform. The organic phase is washed with water, dried over sodium sulphate and evaporated. There is obtained 2-fluoro-10,11-dihydro-dibenzo[b,f]thiepin-10-ol which melts at 110°-113° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04006145 |
| Source dataset | uspto-grants-1977_02 |
| ORD ID | ord-34311e9153b34d66b7b6494a291a172e |
| Source note | uspto-grants-1977_02 |